Libyan leader Moammar Gadhafi escaped a NATO missile strike in Tripoli on Saturday, but his youngest son and three grandchildren under the age of 12 were killed, a government spokesman said.
The strike, which came hours after Gadhafi called for a cease-fire and negotiations in what rebels called a publicity stunt, marked an escalation of international efforts to prevent the Libyan regime from regaining momentum.
Rebels honked horns and chanted "Allahu Akbar" or "God is great" while speeding through the western city of Misrata, which Gadhafi's forces have besieged and subjected to random shelling for two months, killing hundreds. Fireworks were set off in front of the central Hikma hospital, causing a brief panic that the light would draw fire from Gadhafi's forces.
The attack struck the house of Gadhafi's youngest son, Seif al-Arab, when the Libyan leader and his wife were inside. White House spokesman Shin Inouye declined to comment on the developments in Libya, referring questions to NATO.
The alliance acknowledged that it had struck a "command and control building in the Bab al-Azizya neighborhood" Saturday evening, but it could not confirm the death of Gadhafi's son and insisted all its targets are military in nature and linked to Gadhafi's systematic attacks on the population.
The commander of the NATO operation, Canadian Lt. Gen. Charles Bouchard, said he was aware of unconfirmed reports that some Gadhafi family members may have been killed and he regretted "all loss of life, specially the innocent civilians being harmed as a result of the ongoing conflict."
Seif al-Arab Gadhafi, 29, was the youngest son of Gadhafi and brother of the better known Seif al-Islam Gadhafi, who had been touted as a reformist before the uprising began in mid-February. The younger Gadhafi had spent much of his time in Germany in recent years.
Gadhafi's children had been increasingly engaged in covering up scandals fit for a "Libyan soap opera," including negative publicity from extravagant displays of wealth such as a million-dollar private concert by pop diva Beyonce, according to a batch of diplomatic cables released by the secret-spilling WikiLeaks website.
But Seif al-Arab remained largely in the shadows, although he had a penchant for fast cars and partying when outside Libya.
Moammar Gadhafi and his wife were in the Tripoli house of his 29-year-old son when it was hit by at least one bomb dropped from a NATO warplane, according to Libyan spokesman Moussa Ibrahim.
"The leader himself is in good health," Ibrahim said. "He was not harmed. The wife is also in good health."
Ibrahim would not give the names of the three children killed, except to say they were nieces and nephews of Seif al-Arab and that they were younger than 12. He said they are not releasing the names yet to protect the privacy of the family.
He said the compound that was hit was in the Garghour neighborhood.
"It seems there was intelligence that was leaked. They knew about something. They expected him for some reason. But the target was very clear, very, very clear. And the neighborhood, yes of course, because the leader family has a place there, you could expect of course it would be guarded, but it is a normal neighborhood. Normal Libyans live there," he said.